We’re thrilled to share our latest article in PLOS Pathogens: 

"The rise of fungal G-protein coupled receptors in pathogenesis and symbiosis"

This work highlights the latest insights into GPCRs in fungi, revealing how these versatile receptors contribute to both pathogenic and symbiotic interactions. We explore their evolution, signaling mechanisms, and emerging roles across diverse fungal lifestyles.

Read the full article here

New insights into unconventional secretion by Sanchi et al.

Our new study by Sanchi et al. uncovers how the fungal protein Jps1 directs unconventional secretion by binding specific membrane lipids. Sanchi and team show that Jps1’s interaction with PI(4,5)P₂ is essential for exporting the chitinase Cts1 during cell division. This work highlights a novel lipid-based mechanism in non-classical secretion pathways, with potential relevance across fungi and higher organisms. Read the full story here

How do modular RNA-binding proteins engage with mRNA networks?

Together with an interdisciplinary team, Nina has discovered how modular RNA-binding protein (RBPs) fine-tune mRNA regulation to support cell growth. By studying the mRNA transporter Rrm4 in Ustilago maydis, we found that its multiple RNA-binding domains (RBDs) work together in a precise way—some guide RNA interactions, while others determine function. This research reveals how RBPs help regulate key processes like energy production, cell shape, and stability. 

Read the preprint here. Congrats!