Zum Inhalt springenZur Suche springen
Publikationen RAB Lab

K. Müntjes, S. K. Devan, A. Reichert and M. Feldbrügge (2021) Linking transport and translation of mRNAs with endosomes and mitochondria. EMBO Rep. e52445 online ahead print
doi      PubMed

L. Romero-Aguilar, M. Esparza-Perusquía, T. Langner, G. García-Cruz, M. Feldbrügge, G. Zavala, J.P. Pardo, F. Martínez, O. Flores-Herrera (2021) Deletion of the natural inhibitory protein Inh1 in Ustilago maydis has no effect on the dimeric state of the F1FO-ATP synthase but increases the ATPase activity and reduces the stability. BBA Bioenerg. 1862: 148429

K. P. Hussnaetter, M. Philipp, M. Feldbrügge, K. Müntjes and K. Schipper (2021) Controlling Unconventional Secretion for Production of Heterologous Proteins in Ustilago maydis through Transcriptional Regulation and Chemical Inhibition of the Kinase Don3. J. Fungi 7: 179
doi      PubMed

J. Lee, Y.-M. Shi, P. Grün, M. Gube, M. Feldbrügge, H. Bode, and F. Hennicke (2020) Identification of feldin, an antifungal polyine from the beefsteak fungus Fistulina hepatica. Biomol. 10: 1502
doi     PubMed

S. Kubicki, I. Bator, S. Jankowski, K. Schipper, T. Tiso, M. Feldbrügge, L.M. Blank, S. Thies and K.-E. Jaeger (2020). A straightforward assay for screening and quantification of biosurfactants in microbial culture supernatant. Front. Bioeng. Biotechnol. 8: 958
doi      PubMed

J. Lee, F. Hilgers, A. Loeschke., K.E. Jaeger, and M. Feldbrügge (2020) Ustilago maydis serves as a novel production host for the synthesis of plant and fungal sesquiterpenoids. Front. Microbiol. 11: 1655
doi      PubMed

V. Stein, B. Blank-Landeshammer, K. Müntjes, R. Märker, I. Teichert, M. Feldbrügge, A. Sickmann, and U. Kück (2020) The STRIPAK signaling complex regulates phosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes. PLoS Genet. 16: e1008819
doi      PubMed

S. Kwon, C. Tisserant, M. Tulinski, A. Weiberg# and M. Feldbrügge# (2020) Inside-Out: from endosomes to extracellular vesicles in fungal RNA transport. Fungal Biol. Rev. 34: 89-99
#shared corresponding authorship

K. Müntjes, M. Philipp, L. Hüsemann, N. Heucken, S. Weidtkamp-Peters, K. Schipper, M. Zurbriggen, M. Feldbrügge (2020) Establishing polycistronic gene expression in the model microorganism Ustilago maydis. Front. Microbiol. 11: 1384
doi      PubMed

F. Pan, D. EI-Kashef, R. Kalscheuer, W. E. G. Müller, J. Lee, M. Feldbrügge, A. Mándi, T. Kurtán, Z. Liu, W. Wu and P. Proksch (2020) Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017. Eur. J. Med. Chem. 191: 113159
doi      PubMed

P. Stoffels*, M.J. Müller*, S. Stachurski, M. Terfrüchte, S. Schröder, N. Ihling, N. Wierckx, M. Feldbrügge , K. Schipper# and J. Büchs# (2020). Complementing the intrinsic repertoire of Ustilago maydis for degradation of the pectin backbone polygalacturonic acid. J. Biotechnol. 10: 148-163
* shared first authorship   # shared corresponding authorship
doi      PubMed

J. Aschenbroich, K. Hußnätter, P. Stoffels, T. Langner, S. Zander, B. Sandrock, M. Bölker, M. Feldbrügge and K. Schipper (2019) The germinal centre kinase Don3 is crucial for unconventional secretion of chitinase Cts1 in Ustilago maydis. Biochim. Biophys. Acta Proteins and Proteom. 1867: 140154
doi      PubMed

M. Bäumers, S. Klose, C. Brüser, C. Haag, S. Hänsch, H. Pannen, S. Weidtkamp-Peters, M. Feldbrügge and T. Klein (2019) The auxiliary ESCRT complexes provide robustness to cold in poikilothermic organisms. Biol. Open  8: bio043422
doi      PubMed

S. Jankowski*, T. Pohlmann*, S. Baumann, K. Müntjes, S.K. Devan, S. Zander and M. Feldbrügge (2019) The multi PAM2 protein Upa2 functions as novel core component of endosomal mRNA transport.  EMBO Rep24: e47381
*shared first authorship.
doi      PubMed

H. Harwoko, G. Daletos, F. Stuhldreier, J. Lee, S. Wesselborg, M. Feldbrügge, W. E. G. Müller, R. Kalscheuer, E. Ancheeva and P. Proksch (2019) Dithiodiketopiperazine derivatives from endophytic fungi Trichoderma harzianum and Epicoccum nigrum. Nat. Prod. Res. 2019 Jun 18:1-9
doi      PubMed

C. Haag, T. Klein, and M. Feldbrügge (2019) ESCRT mutant analysis and imaging of ESCRT components in the model fungus Ustilago maydis. Methods Mol. Biol. In: The ESCRT Complex: Methods and Protocols, eds E. Culetto and R. Legouis, Springer Science & Buisness Media New York,  p251-271
doi      PubMed

J. Müller*, T. Pohlmann*, and M. Feldbrügge (2019) Core components of endosomal mRNA transport are evolutionarily conserved in fungi. Fungal Genet. Biol. 126: 12-16
*shared first authorship.
doi      PubMed

H. J. Courville, L. Frantzeskakis, S. Gul, N. Haeger, R. Kellner, N. Heßler, B. Day, B. Usadel, Y. K. Gupta, H. P. van Esse, A. Brachmann, E. Kemen, M. Feldbrügge and V. Göhre (2019) Smut infection of perennial hosts: the genome and the transcriptome of the Brassicaceae smut fungus Thecaphora thlaspeos reveal functionally conserved and novel effectors. New Phytol. 222: 1474–1492
doi      PubMed

J. Béthune, R.-P. Jansen, M. Feldbrügge* and K. Zarnack* (2019) Membrane-associated RNA-binding proteins orchestrate organelle-coupled translation. Trends Cell Biol. 29: 178-188
*shared corresponding authorship
doi      PubMed

L. Olgeiser, C. Haag, S. Boerner, J. Ule, A. Busch, J. Koepke, J. König, M. Feldbrügge and K. Zarnack (2019) The key protein of endosomal mRNP transport Rrm4 binds translational landmark sites of cargo mRNAs. EMBO Rep. 20: e46588
doi      PubMed

M. J. Müller, S. Stachurski, P. Stoffels, K. Schipper, M. Feldbrügge and J. Büchs (2018) Online evaluation of the metabolic activity of Ustilago maydis on (poly)galacturonic acid. J. Biol. Eng. 34: e1-17
doi      PubMed

M. Terfrüchte*, S. Wewetzer*, P. Sarkari, D. Stollewerk, M. Franz-Wachtel, B. Macek, T. Schlepütz, M. Feldbrügge, J. Büchs, and K. Schipper (2018) Tackling destructive proteolysis of unconventionally secreted heterologous proteins in Ustilago maydis. J. Biotechnol. 284: 37-51
*Shared first authorship.
doi      PubMed

M. Riquelme, J. Aguirre, S. Bartnicki-García, G. H. Braus, M. Feldbrügge, U. Fleig, W. Hansberg, A. Herrera-Estrella, J. Kämper, U. Kück, R. R. Mouriño-Pérez, N. Takeshita and R. Fischer (2018) Fungal morphogenesis, From the polarized growth of hyphae to complex reproduction and infection structures. Microbiol Mol. Biol. Rev. 82: 1-47
doi      PubMed

L. Zhou, T. Obhof, K. Schneider, M. Feldbrügge, U. Nienhaus and J. Kämper (2018) Cytoplasmic transport machinery of the SPF27 homologue Num1 in Ustilago maydis  Sci. Rep. 8: 3611
doi      PubMed

S. Zander, K. Müntjes and M. Feldbrügge (2018) RNA live imaging in the model microorganism Ustilago maydis. Methods in Mol. Biol. RNA detection, ed. I. Gaspar, Humana Press, New York, 1649: 319-335
doi      PubMed

D. Niessing, R.P. Jansen, T. Pohlmann and M. Feldbrügge (2018) mRNA transport in fungal top models. WIREs RNA. 9: e1453
doi Cover doi      PubMed

C. Haag, T. Pohlmann and M. Feldbrügge (2017) The ESCRT regulator Did2 maintains the balance between long-distance endosomal transport and endocytic trafficking. PLoS Genet. 13: e1006734
doi      Pubmed

C. A. Cárdenas-Monroy, T. Pohlmann, G Piñón-Zárate, G. Matus-Ortega, G. Guerra, M. Feldbrügge and J. Pablo Pardo (2017) The mitochondrial alternative oxidase Aox1 is needed to cope with respiratory stress but dispensable for pathogenic development in Ustilago maydis. PLoS ONE 12: e0173389
doi      PubMed

S. Baumann, S. Zander, S. Weidtkamp-Peters and M. Feldbrügge (2016) Live cell imaging of septin dynamics in Ustilago maydis. Methods in Cell Biol. Septins, ed. A. Gladfelter, Elsevier, 136: 143-149
doi      PubMed

E. Geiser , M. Reindl, L. Blank, M. Feldbrügge, N. Wierckx and K. Schipper (2016) Activating intrinsic CAZymes of the smut fungus Ustilago maydis for the degradation of plant cell wall components. Appl. Env. Mircobiol. 82: 5174-5185
doi      PubMed

S. Zander, S. Baumann, S. Weidtkamp-Peters and M. Feldbrügge (2016) Endosomal assembly and transport of heteromeric septin complexes promote septin cytoskeleton formation. J. Cell Sci. 129: 2778-2792
doi      PubMed

P. Sarkari, M. Feldbrügge and K. Schip­per (2016) The corn smut fungus Ustilago maydis as an alternative expression system for biopharmaceuticals. In: Fungal Biology. Gene expression systems in fungi: advancements and applications. Eds. M. Schmoll and C. Dattenböck. Springer Book Series. 183-200

C. Haag, B. Steuten, and M. Feldbrügge (2015) Membrane-coupled mRNA trafficking in fungi. Annu. Rev. Microbiol. 69: 265-281. doi

T. Pohlmann, S. Baumann, C. Haag, M. Albrecht and M. Feldbrügge (2015) A FYVE zinc finger domain protein specifically links mRNA transport to endosome trafficking. eLife 2015;10.7554/eLife.06041. doi


S. Baumann, N. Takeshita, N. Grün, R. Fischer and M. Feldbrügge (2015) Live cell imaging of endosomal trafficking in fungi. Methods in Mol. Biol., Membrane Trafficking: 2nd edition, ed. Bor Luen Tang, Springer Science&Business Media New York, 1270: 347-363. doi

R.-P. Jansen, D. Niessing, S. Baumann, and M. Feldbrügge (2014) mRNA transport meets membrane traffic. Trends in Genet. 30: 408-417. doi

C. Buerth, F. Kovacic, J. Stock, M. Terfrüchte, S. Wilhelm, K.E. Jaeger, M. Feldbrügge, K. Schipper, J.F. Ernst and D. Tielker (2014) Uml2 is a novel CalB-type lipase of Ustilago maydis with phospholipase A activity. Appl. Microbiol. Biotech. 98: 4963-4973. doi

S. Baumann, J. König, J. Koepke and M. Feldbrügge (2014) Endosomal transport of septin mRNA and protein indicates local translation on endosomes and is required for correct septin filamentation. EMBO Rep. 15:94-102. doi

M. Terfrüchte, B. Jöhnk, R. Fajardo-Somera, G. Braus, M. Riquelme, K. Schipper and M. Feldbrügge (2013) Establishing a versatile Golden Gate cloning system for genetic engineering in fungi. Fungal Genet. Biol.  advanced online publication

V. Göhre, C. Haag and M. Feldbrügge (2013) RNA biology in fungal phyto­­pathogens. PLoS pathol. 9(10): e1003617 doi

M. Feldbrügge, R. Kellner and K. Schipper (2013) The biotechnological use and potential of plant pathogenic smut fungi  Appl. Micobiol. Biotech. 97(8): 3253-3265. doi

Heinrich-Heine-Universität Düsseldorf: Unconventional protein secretion. Erfinder: Feldbrügge, Michael. Anmeldung: 04.10.2012. PCT/EP2012/069603, Veröffentlichungsschrift: 11.04.2013. WO 2013/050458

V. Göhre, E. Vollmeister, M. Bölker and M. Feldbrügge (2012) Microtubule-dependent membrane dynamics in Ustilago maydis: trafficking and function of Rab5a-positive endosomes. CIB 5: 482-487. doi

J. Stock, P. Sarkari, S. Kreibich, T. Brefort, M. Feldbrügge and K. Schipper (2012) Applying unconventional secretion of the endochitinase Cts1 to export heterologous proteins in Ustilago maydis. J. Biotech. 161: 80-91

S. Baumann, T. Pohlmann, M. Jungbluth, A. Brachmann and M. Feldbrügge (2012) Kinesin-3 and dynein mediate microtubule-dependent co-transport of mRNPs and endosomes. J. Cell Sci. 125: 2740-2752

E. Vollmeister, K. Schipper and M. Feldbrügge (2012)  Microtubule-dependent mRNA transport in the model microorganism Ustilago maydis. RNA Biol. 9: 1-8 

E. Vollmeister, K. Schipper, S. Baumann, C. Haag, T. Pohlmann, J. Stock and M. Feldbrügge (2012) Fungal development of the plant pathogen Ustilago maydis. FEMS Microbio Rev. 36: 59-77

R. Kellner, E. Vollmeister, M. Feldbrügge and D. Begerow (2011) Interspecific sex in grass smuts and the genetic diversity of their pheromone-receptor system. PLoS Genet. 7: e1002436 doi 10.1371/journal.pgen.1002436

J. Koepke, F. Kaffarnik, C. Haag, K. Zarnack, N.M. Luscombe, J. König, J. Ule, R. Kellner, D. Begerow and M. Feldbrügge (2011) The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1. Mol. Cell. Proteom. M111.011213-1-15

Heinrich-Heine-Universität Düsseldorf:  Protein production in filamentous fungi. Erfinder: Feldbrügge, Michael. Anmeldung: 29.03.2011. PCT/EP2011/054793, Veröffentlichungsschrift: 06.10.2011. WO 2011/120952

E. Vollmeister and M. Feldbrügge (2010) Posttranscriptional control of growth and development in Ustilago maydis Curr. Op. Microbio. 13: 693-699

K. Zarnack and M. Feldbrügge (2010) Microtubule-dependent mRNA transport in fungi. Euk. Cell. 9: 982-990

L.A. Casselton and M. Feldbrügge (2010) Mating and sexual morphogenesis in basidiomycete fungi. In: Cellular and Molecular Biology of Filamentous Fungi (K. Borkovich and D. Ebbole, eds.), ASM Press, Washington D.C., p. 536-551

E. Vollmeister, C. Haag, K. Zarnack, S. Baumann, J. König, G. Mannhaupt and M. Feldbrügge (2009) Tandem KH domains of Khd4 recognise AUACCC and are essential for regulation of morphology as well as pathogenicity in Ustilago maydis. RNA 15: 2206-2218

J. König, S. Baumann, J. Koepke, T. Pohlmann, K. Zarnack, and M. Feldbrügge (2009) The fungal RNA-binding protein Rrm4 mediates long-distance transport of ubi1 and rho3 mRNAs. EMBO J. 28: 1855 - 1866

K. Zarnack, H. Eichhorn, R. Kahmann, and M. Feldbrügge (2008) Pheromone-regulated target genes respond differentially to MAPK phosphorylation of transcription factor Prf1. Mol. Microbiol. 69: 1041-1053

M. Feldbrügge, K. Zarnack, E. Vollmeister, S. Baumann, J. Koepke, J. König, M. Münsterkötter, and G. Mannhaupt (2008) The posttranscriptional machinery of Ustilago maydis. Fungal Genet. Biol. 45: S40-S46

K. Zarnack and M. Feldbrügge (2007) mRNA trafficking in fungi. Mol. Gen. Genom. 278: 347-359

J. König, C. Julius, S. Baumann, M. Homann, H.U. Göringer and M. Feldbrügge (2007) Combining SELEX and yeast three-hybrid system for the in vivo selection and classification of RNA aptamers. RNA 13: 614-622

P. Becht, J. König, and M. Feldbrügge (2006) The RNA-binding protein Rrm4 is essential for polarity in Ustilago maydis and shuttles along microtubules. J. Cell Sci. 119: 4964-4973

J. Kämper, R. Kahmann, M. Bölker, L.-J. Ma, T. Brefort, B.J. Saville, F. Banutett, J. W. Kronstad, S. E. Gold, O. Müller, M. H. Perlin, H. A. B. Wösten, R. deVries, J. Ruiz-Herrera, C. G. Reynaga-Pena, K. Snetselaar, M. McCann, J. Perez-Martin, M. Feldbrügge, C. W. Basse, G. Steinberg, J. I. Ibeas, W. Holloman, et al. (2006) Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis. Nature 444: 97-101

K. Zarnack, S. Maurer, F. Kaffarnik, O. Ladendorf, A. Brachmann, J. Kämper, and M. Feldbrügge (2006) Tetracycline-regulated gene expression in the pathogen Ustilago maydis Fungal Genet. Biol. 43: 727-738

M. Feldbrügge, M. Bölker, G. Steinberg, J. Kämper, and R. Kahmann (2006) Regulatory and structural networks orchestrating mating, dimorphism, cell shape, and pathogenesis in Ustilago maydis. In: The Mycota I: growth, differentiation and sexuality (R. Fischer and U. Kües, eds.), Springer-Verlag Berlin Heidelberg, p. 376-391

P. Becht, E. Vollmeister, and M. Feldbrügge (2005) A role for RNA-binding proteins implicated in pathogenic development of Ustilago maydis. Euk. Cell 4: 121-133

M. Feldbrügge, J. Kämper, G. Steinberg, and R. Kahmann (2004) Regulation of mating and pathogenic development in Ustilago maydis. Curr. Op. Microbiol. 7: 666-672

A. Brachmann, J. König, C. Julius, and M. Feldbrügge (2004) A reverse genetic approach for generating gene replacement mutants in Ustilago maydis Mol. Gen. Genom. 272: 216-226

P. Müller, G. Weinzierl, A. Brachmann, M. Feldbrügge, and R. Kahmann (2003) Mating and pathogenic development of the smut fungus Ustilago maydis are regulated by one MAP kinase cascade.  Euk. Cell 2: 1187-1199

F. Kaffarnik, P. Müller, M. Leibundgut, R. Kahmann, and M. Feldbrügge (2003) PKA and MAPK phosphorylation of Prf1 allows promoter discrimination in Ustilago maydis. EMBO J. 22: 5817-5826

Z. Szabó, M. Tönnis, H. Kessler, and M. Feldbrügge (2002) Structure-function analysis of lipopeptide pheromones from the plant pathogen Ustilago maydis. Mol. Gen. Genom. 268: 362-370

M. Feldbrügge, P. Arizti, M.L. Sullivan, P.D. Zamore, J.G. Belasco and P.J. Green (2002) Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells. Plant Mol. Biol. 49: 215-223

G. Loubradou, A. Brachmann, M. Feldbrügge, and R. Kahmann (2001) A homologue of the transcriptional repressor Ssn6p antagonizes cAMP signalling in Ustilago maydis. Mol. Microbiol. 40: 719-730

C. Basse, P. Müller, J. Krüger, C. Aichinger, K. Hansson, A. Brachmann, J. Katzenberger, G. Loubradou, A. Leibbrandt, J. Torreblanca, M. Feldbrügge, and R. Kahmann (2000) Communication between Ustilago maydis and its host plant maize. In: IC-MPMI Congress Proceedings: Biology of Plant-Microbe Interactions Vol. 2 (J.G.M. de Wit, T.Bisseling, W.J. Stiekema, eds.) p.384-389

R. Kahmann, G. Steinberg, C. Basse, M. Feldbrügge, and J. Kämper (2000) Ustilago maydis, the causative agent of corn smut disease. In: Fungal Pathology (J.W.Kronstad, ed.) Kluwer Academic publishers, Dordrecht, pp.347-371

J. Krüger, G. Loubradou, G. Wanner, E. Regenfelder, M. Feldbrügge, and R. Kahmann (2000) Activation of the cAMP pathway in Ustilago maydis reduces fungal proliferation and teliospore formation in plant tumors. Mol. Plant-Microbe Interact. 13: 1034-1040

R. Kahmann, C. Basse, and M. Feldbrügge (1999) Fungal-plant signalling in the Ustilago maydis-maize pathosystem. Curr. Opin. Microbiol. 2: 647-650

P. Müller, C. Aichinger, M. Feldbrügge, and R. Kahmann (1999) The MAP kinase kpp2 regulates mating and pathogenic development in Ustilago maydis. Mol. Microbiol. 34: 1007-1017

M. Feldbrügge, M. Sprenger, K. Hahlbrock, and B. Weisshaar (1997) PcMYB1, a novel plant protein containing a DNA-binding domain with one MYB repeat, interacts in vivo with a light-regulatory promoter unit. Plant J. 11: 1079-1093

M. Feldbrügge, K. Hahlbrock, and B. Weisshaar (1996) The transcriptional regulator CPRF1: expression analysis and gene structure. Mol. Gen. Genet. 251: 619-627